chloroquine ma ku jiraan quinine

mataanaha oo siweyn looga ayaa sidoo kale lagu soo waramayaa in itched, Si kastaba ha ahaatee, oo intaasu waxay ahayd sida ciyaartoyda da'da yar ee aabihii ku isku mid ah iyo hooyaday kuwaas oo aydaan wada xajiin socda maamulka chloroquine. Si kastaba ha ahaatee Waxaa jiray kala duwanaansho u ah gudahood xoogga xajiin ka dib markii la isticmaalayo chloroquine ee daawaynta cudurka duumada. deficiency Insaymkaas u dhiganta dehydrogenase glucose-6-phosphate ayaa lagu helay inuu ka mid noqdo itchers badan non-itchers noqon xad badan.

Waayo, schizoniticides dhiigga, heme waa himilo joogta ah, sida uu yahay ereygu acid folic, iyo gaadiidka electron mitochondrial. isdhexgalka Drug laga yaabaa in la beddelo sida daawooyinka aad shaqayso ama kor u halis aad u saameyn khatar ah. Hayso liiska oo dhan ganacsi aad ka faa'iideysan (oo ay ku jiraan qoro daawooyinka / asbriinka iyo baayacmushtariga dabiiciga ah) iyo waxa ay si wadajir ah ula dhakhtarkaaga iyo shaqaalaha farmasiiga wadaagaan. Ha bilaabin, joojin, ama la bedelo qiyaasta wixii daawo ah la soo baxay oggolaanshaha takhtarka. phosphate Chloroquine waa fasalka ka mid ah daawooyinka loo yaqaan kaneecada iyo amebicides.

Waxaa jira qiyaas ahaan 300 xaaladaha duumada ba'an sanad walba gudahood Maraykanka, wax badan oo ka helay ka safarka si ay goobaha caalamiga ah duumada-gud. duumo ba'an waajib ah in si taxadar leh xididka (IV) daroogada hantibaylihin.

Shakhsiyaadka inta badan ka warbixin la qoto dheer sare ee cuncun mar kasta oo ay isticmaalaan diyaarinta sulphate ah. Dadka qaar caadi in kaniiniga sheegaan cuncun leh baxay cuncun in samaynta isku duro. Tani waxay ka dhigan tahay chloroquine in xoogga cuncun chloroquine ayaa sidoo kale loo dhigi karin ayaay u marayso iyo qaab maamul sidii hore ka baray.

Maraykanka ayaa helay 4 million abuurka cinchona ka Filibiin oo bilaabay ka hawlgala xoqayaa in cinchona ee Costa Rica. Intaa waxaa dheer, waxay bilaabeen miro jilif cinchona duurjoogta iyada oo ergooyinka Cinchona. Tobanaan boqolaal ciidamada Maraykanka ee Africa iyo South Pacific mudan dhintay in la'aanta ah ee quinine.

• Waxyeelooyinka ugu badan waxa ay qaataan dhibaato muruqa, ka maqan oo luma, shuban, iyo finan maqaarka ah.
• doorashooyinka kale ee afka ah waxaa ka mid ah atovaquone-proguanil (Malarone ®), quinine, ama mefloquine.
• Waayo, therapy ee lupus erythematosus cutaneous, dose kala duwan oo la mid ah hore waa 200-afar boqol mg maalin kasta ilaa iyo jawaab-daweynta waxaa lagu gaarayaa.
• Chloroquine waa in aan la isticmaali xaaladahan ilaa faa'iido in ay bukaanka uga imaanya khataraha ka iman kara.

Maxay yihiin kiniiniyada phosphate chloroquine waayo,

isbedel ayaa waxay fure u muuqda in K76T tan ma chloroquine Gooni u adkaysta xanbaarsan lysine ku duurjoogta ah nooca ugu booska 76. Waxaa waajib ah inaad caanka ah in sida caadiga badan Isbedelo kale waa caanka ah ee duumada adkaysi chloroquine, Si kastaba ha ahaatee kaliya K76T ku amino acid isku bedelasho ah waxaa si joogto ah u arkay gudahood duumada chloroquine adkaysi ah. Chloroquine waa in aan la isticmaalo daaweynta ee P. cudurada falciparum ka meelaha iska caabin chloroquine ama duumada dhaca ka cabanaya meesha chloroquine prophylaxis ayaa ku guuldareystay. In kasta oo sheekooyinka kordhaysa ay sabab u tahay iska caabin ah oo noole in chloroquine ee qaybaha qaar ka mid ah dunida oo dhan,, this xusullada daroogada mid ka mid ah baahsan ee daaweynta duumada,. In cilmi markii ugu aasaasiga ah, saamaynta horjeeda daahdaa iyo quinine sida orchitis iyo dheecaan URO-genitaly in jiirka lab soo baaraan.

waa wakiilka caadiga ah hantibaylihin inta badan natiijooyinka sumoobo xad-dhaaf ah marka qaaday in xad dhaafka ah. Chloroquine waa qaab la xidhiidha in quinine iyo quinidine, iyo cardiotoxicity raadiyo ka mid ka mid ah wakiilada waxaa laga yaabaa indistinguishable. waa daroogada ah ee kale ee meelaha duumada-gud yar oo lacag la'aan ah CRPf. Isku chloroquine iyo proguanil waa ikhtiyaar u CRPf markii kaneecada kale ee-line ugu horeysay yihiin.

qaadasho Antirheumatic daahdaa yihiin sare, kuwaas oo loo isticmaalo ka hortagga duumada ka badan. Chloroquine galaa caanaha naaska iyo yeeli doona ilmaha naasnuujinta a. Ha naaska inta aad qaadanaysid daawada la soo baxay hadal ugu horeeyay ee bixiyaha daryeelka caafimaadkaaga. Maamulka Cuntada iyo Dawooyinka The (FDA) marka hore ogol chloroquine in 1949. Xarunta waxay leedahay daciif ah hawl hantibaylihin kala go'lahayn iyo dhaqmi karaan sida inhibitor ah tartan rasmi ah ee ku qabanaya daahdaa in daabbulaha putative.

Quinine markii hore loo isticmaalaa sida daawada duumada iyada oo wakhtigii gumaysiga Hindiya. Ayadoon sida waxaa laga dhex helay, warqadaha aasaasiga ah ee ay la isticmaalo sida duumada ayaa laga diiwaan geliyay 1630 Peru. Waxaa sii loo isticmaalo guryaha hantibaylihin ay ilaa labaatameeyo Sagaal iyo toban ah, marka daawo kale oo ka yar waxyeelo aan la rabin in ay meel qaaday, sida chloroquine. Oo meel jidka, quinine helay waddadiisa cocktails our. dhakhaatiirta qaarkood talo adag loola socdo 4- maxkamad 6-todobaad quinine ee dadka bukaanka ah, kuwaas oo lugo xanuun aan la gargaartay siyaabo kale.

Marka bukaanka u dulqaadan karin daawooyinka afka laga qaato, beddelato dabagal on afka ah daaweynta. Meelaynta of tube nasogastric ama isticmaalka antiemetics waajib tahay in laygu u maleeyeen-saabsan si loo fududeeyo maamulka ee daawaynta afka. artesunate IV laga yaabaa in prepositioned at dooran arrimo CDC ee qaybinta guud ahaan Maraykanka. Marka IV artesunate la sii daayay, isbitaalka codsanaya heli doonaa info la xiriira taas oo mid ka mid ah dad badan oo laba iyo baayacmushtarkaaga waa lagu soo diray, halkaas oo artesunate ee ka yimaada, iyo wakhtiga yimid on garoonka Ahaado.