Yog Steroids zoo tsim nyog qhov uas yuav raug?

A 1992 Kev ntsuam xyuas sab tias AAS yuav ob relieve thiab ua rau melancholy, thiab cessation los yog diminished siv AAS yuav ua rau kev nyuaj siab, Tab sis hu ua rau kev tshawb fawb ntxiv raws li ib lub sij hawm ntawm disparate cov ntaub ntawv. Aas Aas Kas tau pom tias hloov cov ntshav qab zib thiab glucose kam rau ua cov tshev mis. Aas Ces corresponding mus testosterone ntxiv kom qhov uas yuav muaj cardiovascular kab mob los yog coronary artery mob. Acne yog haum ntau cov neeg siv AAS cov neeg siv, Feem coob ntawm stimulation ntawm tus sebaceous glands los elevated testosterone theem. Conversion ntawm testosterone rau DHT yuav accelerate tus ceev ntawm premature baldness rau txiv neej genetically predisposed, Tiam sis testosterone nws tus kheej yuav ua baldness hauv cov poj niam. Testosterone yuav tswj tau niam txiv, Cuaj kaum nws muaj ntxiv irregular prolonged absorption lub sij hawm thiab ntau dua ce hauv enanthate, undecanoate, los sis cypionate ester daim ntawv.

Lawv kuj muaj ib feem stimulatory tej yam rau lub siab los ntawm txoj kev uas lawv ntau yam teebmeem rau ntau central tshee neurotransmitters, antagonism ntawm glucocorticoids, thiab stimulation ntawm lub expansion hormone-insulin zoo li txoj kev loj hlob zoo li txoj kev loj hlob-1 axis. Androgens muaj tau sab nyob rau hauv lub Thirties thiab yuav tsum tau characterised li muaj tau piav raws li androgenic (i.e., virilizing) thiab anabolic (e.g., myotrophic, renotrophic). Lub sij hawm anabolic steroid yuav tau hnub dua rau ib yam tsawg kawg nkaus ntawm lub mus-1940s, Thaum nws tau siv los piav lub tswv yim at-the-time hypothetical lub tswv yim ntawm ib testosterone-derived steroid nrog anabolic teebmeem купить провирон tiam sis tsis muaj yam tsawg kawg nkaus los yog tsis muaj androgenic tau. Tsab cai idea no yog formulated feem ntau raws li tus taus tias steroids muaj piv ntawm renotrophic rau androgenic potency uas txawv considerably, Uas yus tias anabolic thiab androgenic tau tej zaum yuav dissociable. Androgens corresponding mus testosterone, thiab dihydrotestosterone yuav tsum tau rau txoj kev loj hlob ntawm organs nyob rau hauv cov txiv neej reproductive lawv, xws li cov seminal vesicles, epididymis, vas deferens, cwj mem qhuav thiab prostate. AAS yog testosterone derivatives tsim los maximize cov anabolic tau ntawm testosterone.

• Cov neeg utilizing anabolic steroids txhim khu cov nqaij ntshiv thiab ntaus pob ncaws pob efficiency yog nyob deb dua yuav muaj ntsiab lus nrog lawv reminiscence, Raws li kev tshawb fawb tshiab los ntawm Northumbria University.
• Txawm li cas los, Txoj kev soj ntsuam twb tsis muaj peev xwm txiav txim seb tus txhais thiab tej yam kev sib raug zoo ntawm lub puas hawv zoo tau teeb meem thiab steroid siv.
• Nyob rau hauv ib daim ntawv ntsuam xyuas, Hom tseem aas Kiv ib koob tshuaj kuaj (AAS) hom tshuaj kuaj pom muaj 500-1,000 mg ib as thiv twg.
• Ib qhov zoo tshaj yuav yog tias soj ntsuam ntawm tsis siv lub siab 'supraphysiological' koob tsim nyog mus cuag cov nqaij-tsev tej yam (Siv Lukas, Graham, Schultz thiab Mayo-Smith Lukas, 2003).
• DEA notes tias, Raws li feem ntau cov chaw tuav cov khoom no yog Internet feem ntau raws li, Nws tseem nyuam qhuav txog unimaginable rau precisely quantify pes tsawg tus neeg tuav tej yam khoom thaum twg muab sij hawm.

Muaj ob yam tshuaj substitutions los testosterone uas tshwm sim nyob rau hauv cov formulation ntawm synthetic steroids . Esterification ntawm cov pab pawg neeg 17-β-hydroxyl ua tus molecule ntau hydrophobic thiab ntev kawg . Duration ntawm tsab ntawv tsa suab tej zaum yuav ntxiv enhanced yog txhaj nyob rau hauv ib cov lus teb roj teb .

Anabolic Steroids rau tsiaj

Curiosity yog tias ntau heev li 50% luv nqi nyob rau hauv lipoprotein , proven kom muaj ib qhov tob correlation nrog deposition hauv vascular phab ntsa, Tau raug cai los ntawm steroid siv . Tus cardiovascular nyhuv ntawm no steroid-induced txo hauv lipoprotein coupled nrog considerably txo HDL yog tsis paub . Qhov kev ua kom ib ce muaj zog-induced los ntawm aerobic coaching rau lipids tsis tshwm sim kom muaj lub hwj huam rau offset lub steroid-induced poob hauv HDL roj . Qhov txheeb xyuas tau ntawm anabolic steroids rau ldl roj thiab lipoproteins zoo li reversible, Tiam sis yuav kawg rau ib lub limtiam twg los tau tom qab siv . Txawm hais tias muaj cov theoretical uas yuav muaj cardiovascular kab mob vim tau rau ntawm daim di ncauj los ntawm anabolic steroid siv, Kev nce rau general mortality thiab cardiovascular txheej xwm muaj tsis tau muab teev tseg rau cov neeg siv anabolic steroids ntawm therapeutic doses . [tshiab]Anabolic-androgenic steroids, Feem ntau hu ua "anabolic steroids", yog synthetic tej yam khoom uas zoo li txiv neej intercourse hormones (e.g., tshuaj kuaj). Ntxiv cov kev pab cuam ntawm anabolic steroids yog cov khoom los tiv thaiv catobolic zog, Siv ceev xwmphem ntaub so ntswg breakdown feem ntau yog mob uas muaj ntau dua thiab loj depth yam (i.e. nyob deb li cas, nyhav, zaum puav mas, li ntawd.).

Nqaij ntshiv, Anabolic steroids tswj lub transcription ntawm lub hom phaj noob uas tswj lub buildup ntawm DNA hauv skeletal nqaij yuav tsum tau rau cov nqaij ntshiv. Tus identical act ntxiv launched ntxiv stringent controls uas muaj ntau dua felony txim txhaum rau offenses uas muaj cov unlawful tis ntawm AAS thiab tib neeg txoj kev loj hlob hormone. Thaum ntxov Kwvyees li xyoo 1990, Tom qab AAS yim tau teem tseg nyob hauv teb chaws As Mes Lis Kas, Ob peb pharmaceutical tuam txhab uas muag tso tseg tsis manufacturing los yog advertising lub merchandise nyob rau hauv peb, ua ke nrog Ciba, searle, Syntex, thiab lwm cov neeg. Nyob rau hauv tej yam tshuaj uas siv tshuaj, Aas Kiv yuav txhais tau hais tias muaj tej yam tshuaj los yog hormonal tshuaj thiab pharmacologically hais txog testosterone uas txhawb cov nqaij ntshiv kev kawm. Tsab cai yog amended los ntawm cov Anabolic Steroid tswj act of 2004, Uas ntxiv prohormones rau daim ntawv uas tswj tej yam khoom, Nrog tej yam los ntawm lub ib hlis ntuj 20, 2005. Olympic pab kws kho mob John Ziegler labored nrog synthetic chemists los tsim ib AAS nrog txo qis thiabrogenic teebmeem.

Vim li cas cov neeg misuse Anabolic Steroids?

Kev nce rau plasma theem ntawm cov enzymes muaj kev cuam tshuam hepatocellular harm los yog tsawg kawg yog elevated permeability ntawm lub hepatocellular membrane. Steroid-induced, transient elevation ntawm cov enzyme ntau yam yog qhia rau feem ntau yog nyob rau hauv ntau yam ntawm ob mus rau 3 Tej zaum muaj nyob rau hauv asymptomatic subjects . Dickerman et al. Pom tias qoj subjects nyob rau hauv lawv kev tshawb fawb muaj elevations ntawm tsim kinase thiab AST, tiam sis tsis GGT, Zoo ib yam nrog rau cov nqaij ntshiv ntawm kev ua kom ib ce muaj zog ntawm steroid siv. Aspartate aminotransferase yog ib tug ntau dua marker ntawm cov nqaij mob dua ALT . Cov neeg uas hepatic puas yuav muaj elevations ntawm tus enzyme particular rau lub siab, GGT nrog AST thiab ALT, tiam sis tsis CK .

Medterms Medical Dictionary

Direct clotting hais tej zaum yuav txo tau kev nce rau hauv lub sij hawm prothrombin. Rau cov neeg mob concomitant anticoagulant remedy, qhov no yuav ua rau los ntshav. AASs trigger yuav ua rau hemoglobin thiab hematocrit thiab siv ntau zaus ntawm anemia, Tab sis yog lub tsev kho mob yuav tsum paub txog tej zaum rau polycythemia. [tshiab]Stanozolol yog ib tug nyob AAS, Vim lub stability afforded los ntawm cov 3,2 pyrazole pawg rau lub A-nplhaib, Uas heev txhim khu thiabrogen receptor binding. Tus thib ob carbon substitution nrog oxygen yog hais tias yuav ua kom cov steadiness ntawm cov pab pawg neeg 3-keto thiab zoo kawg li txhim khu nws ib feem anabolic. Aas No yog anabolic heev, Muaj me ntsis androgenic nyhuv ntawm ib koob tshuaj therapeutic. 5AR tsis txiav rov qab oxandrolone rau ib tug muaj zog thiabrogen, thiab ua ib DHT spinoff, Nws tsis tau aromatized.

Ze li ntawm 20 xyoo, Nws yog assumed tias AAS exerted tseem ceeb tau nyob rau hauv tej hwj huam ncaws pob. Ib randomized tshuaj mus sib hais pom hais tias nws, cuaj kaum, Uas txawm nyob novice ncaws pob ib 10 lub limtiam zog coaching program nrog nws cov lus los ntawm testosterone enanthate ntawm 600 mg/lub limtiam yuav txhim khu hwj huam ntau dua coaching ib leeg kheej. Qhov koob no yog txaus los considerably txhim kho cov nqaij ntshiv pawg txheeb ze rau placebo txawm nyob rau hauv subjects uas yeej tsis qhia txhua.